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29 July 2004

Sosei Co. Ltd.

NNOUNCEMENT OF MOVEMENT IN MAJOR SHAREHOLDERS

[Tokyo, Japan/London, UK]
Sosei Co. Ltd., a Japanese biopharmaceutical company, announces the movement in its major shareholders holding more than 5% of the shares as of 29 July.

- Reasons of the movement
  1. Increase of the total number of capital stock due to the new shares issued upon IPO.
  2. Share offering by the concerned major shareholder upon IPO

- Concerned Holder of the Movement
  Name: Shinichi Tamura
  Address: Satoyamabe, Matsumoto, Nagano Pref. Japan

- Changed items of the concerned shareholder

	Number of the voting rights (number of shares)	Percentage of its voting rights in the total shareholders	Majority rank
Before movement (28 July 2004)	4,845	10.27%	1st
After movement (29 July 2004)	3,645	5.95%	2nd

Note 1:	The 1st major shareholder after movement is the Tokyo Marine and Fire Securities Insurance, Ltd. (4,000 of the voting rights, 6.53% of the total).
Note 2:	The number of all-issued stock is 61,220.